产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction
KCI807 is a cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction. KCI807 interrupts association of the androgen receptor (AR) with transcription activator ELK1 (ETS family transcription factor ELK1). It potently suppresses growth of enzalutamide-resistant prostate cancer tumor xenografts in rodents.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | 0.2 mg/mL (DMSO:EtOH (2:1),clear, warmed, clear colorless solution) |
| storage temp. | room temp |
| SMILES string | [o]1c2c([c](cc1c3cc(ccc3)O)=O)c(ccc2)O |
| InChI key | SZMQXDYEGKRZDG-UHFFFAOYSA-N |
