产品介绍
Product Description
General description
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Immunogen
A synthetic phosphorylated peptide around Y1474 of human GRIN2B (NP_000825.2).
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | human, rat, mouse |
| concentration | 0.59 mg/mL |
| technique(s) | immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000 |
| UniProt accession no. | Q13224 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pTyr1474) |
| Gene Information | human ... GRIN2B(2904) |
