产品介绍
Product Description
Biochem/physiol Actions
CAM833 is a potent and selective inhibitor of RAD51:BRCA2 interaction that inhibits RAD51 foci formation in A549 non-small cell lung carcinoma (NSCLC) cells. CAM833 suppresses extended RAD51 filament assembly. It potentiates the DNA damage by ionizing radiation in cells.
potent and selective inhibitor of RAD51:BRCA2 interaction
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | FC1=CC=C(N=C(C(NCC(N2[C@H](C(N[C@H](C3=C(Cl)C=C(OC)C=C3)C)=O)C[C@@H](O)C2)=O)=O)C=C4)C4=C1 |
| InChI key | PMUWBFKMLGLUTF-KNUWZQJKSA-N |
