General description
Anti-Acetyl-CoA Carboxylase Antibody detects endogenous levels of total Acetyl-CoA Carboxylase protein.
Acetyl-CoA carboxylase 1 (ACC1) is a cytosolic enzyme. It is located on human chromosome 17q12.
Immunogen
The antiserum was produced against synthesized peptide derived from human Acetyl-CoA Carboxylase.
Immunogen Range: 46-95
Biochem/physiol Actions
Acetyl-CoA carboxylase 1 (ACC1) catalyzes the rate-limiting step in de novo fatty acid biosynthesis. Acetyl-CoA is carboxylated to malonyl-CoA with the help of acetyl-CoA carboxylase (ACACA) in the fatty acid synthesis pathway. ACC1 is essential for the assembly of invadopodia.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 265 kDa |
| species reactivity | mouse, rat, human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:5000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000 |
| NCBI accession no. | Q13085 |
| UniProt accession no. | Q13085 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ACACA(31) |
