产品介绍
Product Description
General description
Eltoprazine, a serotonergic agent, possesses specific anti-aggressive (serenic) properties in various animal models without triggering sedation, motor disturbances, or muscle relaxation.
Biochem/physiol Actions
Eltoprazine hyrochloride is a serotonin 5-HT1A/1B receptor agonist that has been shown to reduce L-DOPA-induced dyskinesias in in experimental models of Parkinson′s Disease and in human patients. It has Ki values for 5-HT1A, 5-HT1B and 5-HT1C receptors of 40 nM and 52 nM, respectively.
Serotonin 5-HT1A/1B receptor agonist
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | H2O: 10 mg/mL, clear |
| web metadata keyword.default | 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride,Eltoprazine hydrochloride 98206-09-8,Eltoprazine hydrochloride animal model studies,Eltoprazine hydrochloride anti-aggressive agent,Eltoprazine hydrochloride chemical,Eltoprazine hydrochloride for Parkinson′s Disease research,Eltoprazine hydrochloride in large quantities,Eltoprazine hydrochloride pharmacological properties,Eltoprazine hydrochloride purity grade,Eltoprazine hydrochloride research chemical,Eltoprazine hydrochloride serotonin receptor agonist,Eltoprazine hydrochloride titration reagent,Eltoprazine hydrochloride,Sigma-Aldrich Eltoprazine hydrochloride |
| storage temp. | room temp |
| SMILES string | [H]Cl.C1(OCCO2)=C2C(N3CCNCC3)=CC=C1 |
| InChI | 1S/C12H16N2O2.ClH/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12;/h1-3,13H,4-9H2;1H |
| InChI key | JFSOSUNPIXJCIX-UHFFFAOYSA-N |
