General description
The antibody MEM-01 reacts with CD22 (BL-CAM), a 130 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed in the cytoplasm of pro-B and pre-B lymphocytes, and on the surface of mature and activated B lymphocytes; it is lost on plasma cells, peripheral blood T lymphocytes, granulocytes and monocytes. The antibody MEM-01 cross-blocks the antibody OTH228 that recognizes uniquely epitope "E"; it does not cross-block antibodies RFB-4, CLB22/1 and CLB-BLy1.
Immunogen
Raji Burkitt′s lymphoma cell line
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:500. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Features and Benefits
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Physical form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | biotin conjugate |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | MEM-01, monoclonal |
| form | buffered aqueous solution |
| species reactivity | nonhuman primates, human |
| concentration | 1 mg/mL |
| technique(s) | flow cytometry: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_001185099.1 |
| UniProt accession no. | P20273 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CD22(933) |
