产品介绍
Product Description
General description
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Immunogen
A synthetic phosphorylated peptide around S276 of human NF-kB p65 (NP_068810.3).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
技术参数
Specifications
| biological source | rabbit |
| Quality Level | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 58, 59, 60 |
| species reactivity | human, rat, mouse |
| concentration | 0.95mg/ml |
| technique(s) | immunofluorescence: 1:20-1:50,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:2000 |
| UniProt accession no. | Q04206 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer276 ) |
| Gene Information | human ... RELA(5970) |
