General description
ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist. This antibody will not cross-react with the zinc transporter ZIP10.
Immunogen
ZIP11 antibody was raised against a 15 amino acid peptide near the center of the human ZIP11.
Features and Benefits
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Physical form
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500001.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | rat, human, mouse |
| technique(s) | immunohistochemistry: suitable,indirect ELISA: suitable,western blot: suitable |
| NCBI accession no. | EAW89107 |
| UniProt accession no. | Q8N1S5 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SLC39A11(201266) |
