Application
Glycophorin is the major sialylated protein of the erythrocyte membrane. Product A9791 is asialoglycophorin from human blood type MN. Glycophorin has been inserted into target cells, by electropulsation, to study resistance to natural killer cells .
Biochem/physiol Actions
M and N active glycopeptides have identical amino acid sequences, except at residues 1 and 5, and glycosylated residues 2 to 4, which contain approximately 5 sialic acid groups. The removal of sialic acid from glycophorin destroys M and N activity. Glycophorin A may be involved in the resistance of target cells to natural killing.
Other Notes
Predominantly asialoglycophorin A
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
| biological source | human blood (type MN) |
| Quality Segment | 200 |
| form | lyophilized powder |
| concentration | 30.00-50.00% (Lowry) |
| storage temp. | −20°C |
