General description
Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
FGF18 (fibroblast growth factor 18) is a member of the paracrine-acting FGF8 subfamily. It is expressed in the perichondrium and joints of developing long bones. FGF18 is a 21.2 kDa glycosylated secretory protein, that is structurally similar to FGF8 and FGF17. It is mapped to human chromosome 5q35.1. Anti-FGF18 Antibody detects endogenous levels of total FGF18 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human FGF18.
Immunogen Range: 151-200
Biochem/physiol Actions
FGF18 (fibroblast growth factor 18) plays an important role in the skeletal development of the embryonic and adult organism. It is associated with colorectal and ovarian cancer. FGF18 participates in cell proliferation and differentiation during osteogenesis and chondrogenesis. It is essential for the growth of bone, cartilage, hair, cardiovasculature and alveolus.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 23 kDa |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:40000,immunofluorescence: 1:100-1:500,immunohistochemistry: 1:50-1:100 |
| NCBI accession no. | O76093 |
| UniProt accession no. | O76093 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... FGF18(8817) |
