产品介绍
Product Description
Biochem/physiol Actions
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs.
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs. TRPV4 is a nociceptor playing an important role in inflammatory and neuropathic mechanical hyperalgesia in rodent models apparently specifically activated under pathological conditions.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | light yellow to light tan |
| solubility | DMSO: ≥10 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | [O-][N+](=O)c1cc(Cl)ccc1S(=O)(=O)N2CCN(CC2)Cc3ccccc3 |
| InChI | 1S/C17H18ClN3O4S/c18-15-6-7-17(16(12-15)21(22)23)26(24,25)20-10-8-19(9-11-20)13-14-4-2-1-3-5-14/h1-7,12H,8-11,13H2 |
| InChI key | ZNLVYSJQUMALEO-UHFFFAOYSA-N |

