产品介绍
Product Description
Biochem/physiol Actions
Inactive analog of and negative control for the potent and selective TGF-β type I receptors ALK1/ACVRL1 & ALK2/ACVR1 inhibitor M4K2234.
M4K2234NC is an inactive analog of and the recommended negative control for the potent and selective TGF-β type I receptors ALK1/ACVRL1 & ALK2/ACVR1 inhibitor M4K2234 (ALK1/2 IC50 >10 μM/ 5.69 μM by cellular NanoBRET assays; IC50 = 83 nM/13 nM using M4K2234).
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear (Warmed) |
| storage temp. | 2-8°C |
| SMILES string | CC(C)N1CCN(CC1)C2=CC=C(C3=C(C)C(C4=CC(OC)=C(C(N5CCCC5)=O)C(F)=C4)=CN=C3)C=C2 |
| InChI key | WFJOMSKCDAOJBT-UHFFFAOYSA-N |
