产品介绍
Product Description
Application
Hck is a protein-tyrosine kinase that is expressed in hemopoietic cells. It is used in leukemia research .
Biochem/physiol Actions
Hck is a member of the Src tyrosine kinase family. Hck has been shown to associate with and be activated by Bcr-Abl, which is a protein-tyrosine kinase that is expressed in chronic myelogenous leukemia .
Physical form
Supplied as a solution in 50 mM Tris HCl, pH 7.4, 1 mM EDTA and 1 mM DTT
Other Notes
One unit will phosphorylate 1.0 picomole of Tyr15 of the peptide substrate pcdc2 6-20 per minute at 30 °C at pH 7.4.
技术参数
Specifications
| recombinant | expressed in E. coli BL21 |
| Quality Segment | 200 |
| form | solution |
| specific activity | 1-2 unit/μg protein |
| packaging | vial of ≥200 units |
| relevant disease(s) | cancer (leukemia) |
| shipped in | dry ice |
| storage temp. | −70°C |
