产品介绍
Product Description
Application
Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems.
Biochem/physiol Actions
α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS).
技术参数
Specifications
| Quality Segment | 100 |
| solubility | H2O: 50 mg/mL |
| SMILES string | Cl.C1CN=C(N1)C2COc3ccccc3O2 |
| InChI | 1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H |
| InChI key | MYUBYOVCLMEAOH-UHFFFAOYSA-N |
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
