产品介绍
Product Description
Biochem/physiol Actions
Boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3).
AN3661 is a boron containing antimalarial agent that targets Plasmodium falciparum CPSF3 (cleavage and polyadenylation specific factor 3). AN3661potently inhibits Plasmodium falciparum laboratory-adapted strains (mean IC50=32 nM). Also, AN3661 inhibits T. gondii growth in human cells at low micromolar concentrations.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | OC(CCC1=CC=CC2=C1B(OC2)O)=O |
| InChI | 1S/C10H11BO4/c12-9(13)5-4-7-2-1-3-8-6-15-11(14)10(7)8/h1-3,14H,4-6H2,(H,12,13) |
| InChI key | CEVOKIPNIZQANN-UHFFFAOYSA-N |
