产品介绍
Product Description
Biochem/physiol Actions
EPZ020411 is a potent and selective protein arginine methyltransferase PRMT6 inhibitor (IC50 = 10 nM; PRMT1/8 IC50 = 119/223 nM). EPZ020411 inhibits PRMT6 expression-induced H3R2 methylation in A375 cells (IC50 = 637 nM), but not PRMT1-specific methylmark (IC50 = 7.1 μM).
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | (Oil (syrup)) |
| color | colorless to faint brown |
| storage temp. | -10 to -25°C |
