产品介绍
Product Description
Biochem/physiol Actions
UPGL00004, a BPTES analog, is an orally available, potent and selective inhibitor of glutaminase C (GAC) that potently inhibits the growth of triplenegative breast cancer cells. UPGL00004 directly binds to the allosteric site at GAC.
orally available, potent and selective inhibitor of glutaminase C (GAC)
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to pink |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(CC1=CC=CC=C1)NC(S2)=NN=C2N(CC3)CCC3NC4=NN=C(NC(CC5=CC=CC=C5)=O)S4 |
| InChI | 1S/C25H26N8O2S2/c34-20(15-17-7-3-1-4-8-17)27-23-30-29-22(36-23)26-19-11-13-33(14-12-19)25-32-31-24(37-25)28-21(35)16-18-9-5-2-6-10-18/h1-10,19H,11-16H2,(H,26,29)(H,27,30,34)(H,28,31,35) |
| InChI key | MRYCNTHLPRENBA-UHFFFAOYSA-N |
