产品介绍
Product Description
Biochem/physiol Actions
Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.
Disclaimer
Protect from light.
技术参数
Specifications
| biological source | Streptomyces netropsis |
| Quality Segment | 200 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | faintly yellow |
| solubility | H2O: 1 mg/mL |
| antibiotic activity spectrum | Gram-negative bacteria,Gram-positive bacteria,viruses |
| mode of action | DNA synthesis | interferes |
| storage temp. | −20°C |
| SMILES string | [H]Cl.[H]Cl.NC(CCNC(C1=CC(NC(C2=CC(NC(CNC(N)=N)=O)=CN2C)=O)=CN1C)=O)=N |
| InChI | 1S/C18H26N10O3.2ClH/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22;;/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24);2*1H |
| InChI key | SDRHUASONSRLFR-UHFFFAOYSA-N |
