Immunogen
Synthetic peptide directed towards the middle region of human SLC5A11
Application
Anti-SLC5A11 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.
Biochem/physiol Actions
SLC5A11 is a sodium/glucose cotransporter that uses ion gradients to drive active transport of nutrients, neurotransmitters, osmolytes and ions. It interacts with TNF-α, programmed cell death 1 (PDCD1) and complement component 4 (C4) and may induce apoptosis via the TNF-α - PDCD1 pathway. The gene encoding for this transporter also acts as an autoimmune modifier gene.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: VGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGVL
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 74 kDa |
| species reactivity | horse, mouse, goat, human, guinea pig, rat, bovine, rabbit, dog |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_443176 |
| UniProt accession no. | Q8WWX8 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SLC5A11(115584) |
