General description
Mitochondrially encoded cytochrome c oxidase II (MT-CO2) is a key subunit of cytochrome c oxidase, which is the terminal enzyme involved in the oxidative phosphorylation complexes.
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded cytochrome c oxidase II
Biochem/physiol Actions
Polymorphism in mitochondrially encoded cytochrome c oxidase II (MT-CO2) might alter electron transfer from cytochrome c to the bimetallic center of the catalytic subunit I. Aberrations in MT-CO2 expression has been observed in prostate cancer patients.
The antibody detects endogenous levels of total MT-CO2 protein.
Features and Benefits
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Physical form
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 26 kDa |
| species reactivity | human, mouse |
| concentration | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:10- 1:50,western blot: 1:500-1:2000 (Cell Lysate) |
| isotype | IgG |
| accession no. | P00403 |
| UniProt accession no. | P00403 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... MT-CO2(4513) |
