Immunogen
Synthetic peptide directed towards the C terminal region of human ACVR2B
Application
Anti-ACVR2B antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml.
Biochem/physiol Actions
Activin A receptor, type IIB (ACVR2B) binds activin ligands that promote growth and differentiation via the TGF-β signaling. ACVR2B is expressed in adult hypothalamus and forebrain. Activin receptors IIA and IIB may regulate germ cell proliferation in the human ovary during primordial follicle formation and in mouse testis.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: HDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 33 kDa |
| species reactivity | dog, guinea pig, human, horse, sheep, bovine, rat |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| web metadata keyword.default | 1x PBS buffer Anti-ACVR2B antibody,ACVR2B antibodies for scientific research,ACVR2B antibody Sigma-Aldrich research use,ACVR2B antibody for western blotting,Anti-ACVR2B antibody rabbit western blot,Anti-ACVR2B antibody,Anti-Activin A receptor type IIB antibody,customized Anti-ACVR2B antibody production,high purity Anti-ACVR2B antibody,purified Anti-ACVR2B antibody 0.25µg/ml,rabbit Anti-ACVR2B antibody western blot reagent,research grade Anti-ACVR2B antibody for laboratories,sodium azide preserved Anti-ACVR2B antibody,synthetic peptide ACVR2B antibody application |
| NCBI accession no. | NP_001097 |
| UniProt accession no. | Q13705 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ACVR2B(93) |
