General description
IL-17A (interleukin 17A) is a proinflammatory cytokine of Th17 (helper T cells). It is located on chromosome 6p12.
Immunogen
a 16 amino acid peptide from near the amino-terminus of human IL-17A.
Application
Anti-IL-17 has been used in western blotting and immunohistochemistry.
Biochem/physiol Actions
IL-17A (interleukin 17A) plays a major role in the pathogenesis of autoimmune diseases like multiple sclerosis and rheumatoid arthritis. It also plays a pathogenic role in allergic rhinitis (AR). It helps in the formation of several chemokines and cytokines in airway epithelial cells.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
Other Notes
The action of this antibody can be blocked using blocking peptide SBP4877.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 17 kDa |
| species reactivity | mouse, human |
| technique(s) | indirect ELISA: suitable,western blot: suitable |
| UniProt accession no. | Q16552 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... IL17A(3605) |
