General description
Prostate specific antigen (PSA) is a kallikrein-related serine peptidase that belongs to the chymotrypsin subfamily serine protease. It was originally found in human semen. PSA is also detected in serum correlated to benign and metastatic disease.
Application
Prostate Specific Antigen Substrate has been used to assay recombinant severe acute respiratory syndrome coronavirus-2 viral 3-chymotrypsin-like cysteine protease (SARS-CoV-2 3CLpro).
Biochem/physiol Actions
Prostate specific antigen (PSA). It exhibits chymotrypsin-like activity. PSA is the most abundant protease found in the prostate and secreted into the seminal fluid. It is a useful biomarker for prostate cancer. PSA digests the gel-forming proteins semenogelins I and II in semen. It shows antiangiogenic activity in vitro and in vivo.
| assay | ≥95% (HPLC) |
| form | lyophilized |
| composition | Peptide Content, ≥75% |
| storage condition | protect from light |
| storage temp. | −20°C |
