General description
Anti-SRPK1 Antibody detects endogenous levels of total SRPK1 protein.
Serine-arginine protein kinase 1 (SRPK1) belongs to the SR kinase family. In mammals, SRPK1 is expressed in the central nervous system in a region- and neuron-specific manner. This gene is mapped to human chromosome 6p21.2-p21.3. SRPK1 is also expressed in several normal tissues like testis and pancreas.
Immunogen
The antiserum was produced against synthesized peptide derived from human SRPK1.
Immunogen Range: 521-570
Biochem/physiol Actions
Serine-arginine protein kinase 1 (SRPK1) modulates angiogenesis. Suppressing SRPK1 prevents the development and migration in renal carcinoma cells. In normoxic condition, SRPK1 can increase the migration and invasion of glioma cells.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 92 kDa |
| species reactivity | rat, mouse, human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:40000,western blot: 1:500-1:1000 |
| NCBI accession no. | Q96SB4 |
| UniProt accession no. | Q96SB4 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SRPK1(6732) |
