General description
The folate receptor 1 (FOLR1) gene encodes for folate receptor α protein, a membrane-bound glycoprotein. The FOLR1 gene is mapped on the human chromosome at 11q13.4. Anti-FOLR1 antibody detects endogenous levels of total FOLR1 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human FOLR1.
Immunogen Range: 41-90
Biochem/physiol Actions
Folate receptor α protein binds and facilitates the transport of folate into the cells. This protein acts as a therapeutic target as well as a prognostic marker for various kinds of cancers. Upregulation of the FOLR1 gene is associated with ovarian, lung, breast, brain, colorectal, and gastric cancers.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 29 kDa |
| species reactivity | rat, mouse, human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:1000,western blot: 1:500-1:1000 |
| NCBI accession no. | P15328 |
| UniProt accession no. | P15328 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... FOLR1(2348) |
