General description
The Human sTNF RI (soluble tumor necrosis factor receptor I) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human sTNF RI in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human TNF RI
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Biochem/physiol Actions
Tumour necrosis factor (TNF) receptor superfamily member 1A is a type I single transmembrane glycoprotein. Signal transduction mediated by binding of TNFα regulates inflammatory, immune responses and apoptotic pathway. TNF receptor 1 is implicated in the end-stage renal disease and associated mortality. Mutations in TNF receptor 1 causes autosomal dominant tumor necrosis factor receptor-associated periodic syndrome (TRAPS). Polymorphism in TNF receptor 1 causes multiple sclerosis.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable,capture ELISA: suitable |
| input | sample type serum sample type cell culture supernatant(s) sample type plasma sample type urine |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 1 pg/mL standard curve range: 0.55-400 pg/mL |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... TNFRSF1A(7132) |
