Immunogen
The epitope recognized by PLA0098 maps to a region between residue 4775 and the C-terminus (residue 4829) of human Baculoviral IAP repeat-containing protein 6 using the numbering given in Swiss-Prot entry Q9NR09 (GeneID 57448).
Physical form
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Other Notes
BIRC6/Apollon contains a baculoviral-IAP repeat (BIR) and ubiquitin-conjugating enzyme (UBC) domain and functions in the inhibition of apoptosis. BIRC6/Apollon inhibits apoptosis by ubiquitinating and promoting the proteasomal degradation of SMAC (second mitochondria-derived activator of caspase) and caspase-9.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human, mouse |
| concentration | 1 mg/mL |
| technique(s) | immunohistochemistry: 1:2,000- 1:10,000,immunoprecipitation (IP): 2-10 μg/mg,western blot: 1:2,000-1:10,000 |
| accession no. | Q9NR09 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | rabbit ... BIRC6/Apollon(57448) |
