产品详情

Pyr10,25MG,SML1243-25MG,Sigma

销售价: ¥ 3682.15 / 件
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订货号 0BP0048
品牌型号 SML1243-25MG
货期 询货期
最小订货量 1件
产品介绍 Product Description

Biochem/physiol Actions

Pyr10 is a novel, selective inhibitor of the transient receptor potential channel TRPC3.
Pyr10 is a novel, selective inhibitor of the transient receptor potential channel TRPC3. Pyr10 blocks carbachol-induced calcium entry into TRPC3-transfected HEK293 cells (IC50 = 0.72 μM), with significantly lower activity against STIM1/Orai1 mediated release of calcium from endoplasmic reticulum (store operated calcium entry) in BRL-2H3 cells (IC50 = 13.08 μM).


技术参数 Specifications
Quality Level100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
SMILES stringFC(F)(F)c1[n](nc(c1)C(F)(F)F)c2ccc(cc2)N[S](=O)(=O)c3ccc(cc3)C
InChI keyCVALMMCIOLXHDM-UHFFFAOYSA-N
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