产品介绍
Product Description
Biochem/physiol Actions
BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.
Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.
Other Notes
Lyophilized from 0.1% TFA in H2O
技术参数
Specifications
| Quality Level | 200 |
| assay | ≥97% (HPLC) |
| form | lyophilized powder |
| storage temp. | −20°C |
| SMILES string | S(CC[C@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)C |
| InChI | 1S/C27H50N6O6S/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39)/t18-,19-,20-,21-,22-/m0/s1 |
| InChI key | NHMUTADCTDDWPV-YFNVTMOMSA-N |
