产品介绍
Product Description
Biochem/physiol Actions
FIT-039 is a potent and selective cyclin-dependent kinase 9 (CDK9) inhibitor that binds to the ATP -binding pocket of CDK9 and inhibits the kinase activity of P-TEFb complex. FIT-039 inhibits replication of herpes simplex virus 1 (HSV-1), HSV-2, human adenovirus, and human cytomegalovirus in cultured cells. FIT-039 ointment inhibits formation of skin legion in a mice HSV-1 infection model.
potent and selective cyclin-dependent kinase 9 (CDK9) inhibitor; antiviral agent
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | Fc1cc(c(cc1)N3CCCCC3)NC(=S)c2ccncc2 |
| InChI key | VRKZHYSJZOUICG-UHFFFAOYSA-N |
