General description
KLF13 belongs to a family of transcription factors that contain three classical zinc finger DNA-binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 [PubMed 11087666]).
RFLAT-1/KLF13 (kruppel like factor 13) belongs to the krüppel-like family of transcription factors. This gene is located on human chromosome 15q13.
Immunogen
KLF13 (AAH13946, 31 a.a. ~ 72 a.a) partial recombinant protein.
Sequence
PESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLN
Application
Monoclonal Anti-KLF13 antibody has been used in immunoblotting.
Biochem/physiol Actions
RFLAT-1/KLF13 (kruppel like factor 13) controls the life cycle of papillomavirus in keratinocytes through STAT5 (signal transducer and activator of transcription 5) and IL-8 (interleukin-8). It participates in cardiac gene transcription and heart development.
Physical form
Solution in phosphate buffered saline, pH 7.4
Legal Information
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Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 1D3, monoclonal |
| form | buffered aqueous solution |
| species reactivity | rat, human, mouse |
| technique(s) | indirect ELISA: suitable,western blot: 1-5 μg/mL |
| isotype | IgG2aκ |
| GenBank accession no. | BC010438 |
| UniProt accession no. | Q9Y2Y9 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... KLF13(51621) |
