产品介绍
Product Description
Biochem/physiol Actions
NS3623 is a potent and selective activator of KV11.1 (hERG) and KV4.3 channels. It activates the IKr and Ito currents and exhibits antiarrhythmic activity. NS3623 may also act as a partial blocker of KV11.1 channels.
potent and selective activator of KV11.1 (hERG) and KV4.3 channels; antiarrhythmic
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | FC(F)(F)c1cc(ccc1)NC(=O)Nc2c(cc(cc2)Br)c3[nH]nnn3 |
| InChI | 1S/C15H10BrF3N6O/c16-9-4-5-12(11(7-9)13-22-24-25-23-13)21-14(26)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H2,20,21,26)(H,22,23,24,25) |
| InChI key | JXPULDIATMTIIN-UHFFFAOYSA-N |
