产品介绍
Product Description
Biochem/physiol Actions
Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.
Features and Benefits
This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Disclaimer
Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.
技术参数
Specifications
| Quality Level | 300 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]27/D +12°, c = 1 in methanol(lit.) |
| color | white |
| mp | 227-233 °C (lit.) |
| solubility | ethanol: 1 mg/mL (stable at least a week at 4°C.),DMSO: 10 mg/mL (stable at least six weeks at −20°C.),methanol: 10 mg/mL,H2O: insoluble |
| antibiotic activity spectrum | neoplastics,viruses |
| mode of action | DNA synthesis | interferes |
| storage temp. | 2-8°C |
| SMILES string | [H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4 |
| InChI | 1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1 |
| InChI key | NOFOAYPPHIUXJR-APNQCZIXSA-N |
| Gene Information | human ... POLA1(5422), POLD1(5424), POLG(5428) |
