产品介绍
Product Description
Biochem/physiol Actions
The fos-related antigen 1 (Fra-1, or FosL1: Fos-like antigen 1) is a member of the Fos onco-protein family and a component of AP-1 transcription factor. Similar to other members of the family, Fra-1 contains a leucine zipper domain and a highly conserved C-terminal region. Transcription of Fra-1 gene is regulated by multiple cis-elements and 12-O-tetradecanoylphorbol-13-acetate (TPA). Fra-1 expression is associated with proliferation and invasiveness of breast cancer cells and other cancer cells.
Physical form
Clear and colorless frozen liquid solution
Preparation Note
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.
技术参数
Specifications
| biological source | human |
| recombinant | expressed in insect cells |
| assay | ≥70% (SDS-PAGE) |
| form | frozen liquid |
| mol wt | ~31.2 kDa |
| packaging | pkg of 5 μg |
| storage condition | avoid repeated freeze/thaw cycles |
| concentration | 350 μg/mL |
| color | colorless to clear |
| NCBI accession no. | NM_005438 |
| UniProt accession no. | P15407 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... FOSL1(8061) |
