产品介绍
Product Description
General description
葡萄糖-6-磷酸脱氢酶（G6P DH）具有活性的二聚体形式，其单体和四聚体形式是无活性的。在低NADP+和NADPH水平且在正常条件下，酶以四聚体和二聚体形式存在并保持平衡，而在高NADP +和NADPH水平时，这种平衡转变为无活性的四聚体形式。
Application
作为NADPH的辅因子再循环系统的组分。
Biochem/physiol Actions
葡萄糖-6-磷酸脱氢酶（G6P-DH）参与戊糖磷酸途径。 它能够催化葡萄糖-6-磷酸（G6P）的氧化，产生葡糖酸内酯-6-磷酸，其中NADP+同时接受氢以形成NADPH，从而维持细胞中的NADPH水平。
Features and Benefits
污染物: <0.001% CK，<0.01% GR、HK、6-PGDH和PGluM，<0.002% PGI，<0.002% PGI
在+25℃下约350 U/mg，以葡萄糖-6-磷酸为底物。
Physical form
悬浮于3.2 M硫酸铵溶液中，pH约为6
Preparation Note
活化剂：Mg2+（5至10 mM）
Other Notes
仅用于生命科学研究。不可用于诊断。
技术参数
Specifications
| biological source | yeast |
| form | suspension |
| specific activity | ~350 units/mg protein (At 25 °C with glucose-6-P as the substrate.) |
| packaging | pkg of 1 mL (5 mg/ml) |
| manufacturer/tradename | Roche |
| concentration | ≥0.1-1.0 % (w/w) |
| technique(s) | activity assay: suitable |
| color | white to yellowish |
| optimum pH | 9.2 |
| solubility | water: miscible |
| suitability | suitable for UV spectrophotometry and general use |
| NCBI accession no. | CAA93357 |
| UniProt accession no. | P11412 |
| application(s) | life science and biopharma |
| foreign activity | 6-PGDH <0.0100%,CK <0.00100%,GR <0.0100%,HK <0.0100%,PGI <0.00200%,PGluM <0.0100% |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| Gene Information | Saccharomyces cerevisiae ... ZWF1(855480) |
