General description
Androgen receptor (AR) is a receptor for the androgenic hormones testosterone or dihydrotestosterone and it is a member of the steroid superfamily of ligand-dependent transcription factors. In the absence of androgen, the unligated AR mainly locates in cytoplasm, but translocates to the nucleus upon binding to androgen. Truncated AR variants with loss of C-terminus are common in prostate cancer.
Immunogen
Synthetic peptide from the C-terminus of human androgen receptor protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| recombinant | expressed in proprietary host |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | SP242, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | dog, pig, rat, rabbit, mouse |
| technique(s) | immunohistochemistry: 1:100 |
| isotype | IgG |
| UniProt accession no. | P10275 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... AR(367) |
