General description
Anti-MT-ND1 Antibody detects endogenous levels of total MT-ND1 protein.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
Immunogen
The antiserum was produced against synthesized peptide derived from human MT-ND1.
Immunogen Range: 176-225
Biochem/physiol Actions
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) plays a vital role in the electron transport chain of oxidative phosphorylation (OXPHOS). Mutations in MT-ND1 gene is observed in individuals with LHON (leber′s hereditary optic neuropathy). Mutation in MT-ND1 results in dextrocardia, ventriculoarterial discordance and tricuspid atresia.
Features and Benefits
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Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 35 kDa |
| species reactivity | human |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:40000,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000 |
| NCBI accession no. | P03886 |
| UniProt accession no. | P03886 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... MT-ND1(4535) |
