Immunogen
Gamma-glutamyltransferase 4 precursor recombinant protein epitope signature tag (PrEST)
Application
Anti-GGT7 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem/physiol Actions
GGT7 (γ-glutamyltransferase 7) gene encodes a membrane-bound enzyme involved in the cleavage of glutathione conjugates. It belongs to a family of proteins that function in cell′s detoxification pathway and apoptotic balance. Increased levels of GGT is observed in women with higher risk of gynaecologic cancers and also leads to worse prognosis. The encoded protein interacts with CT120, a plasma membrane-associated protein that is involved in the transport of amino acids and metabolism of glutathione.
Features and Benefits
Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.
Every Prestige Antibody is tested in the following ways:
- IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
- Protein array of 364 human recombinant protein fragments.
Physical form
Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
Other Notes
Corresponding Antigen APREST71922
Legal Information
Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| product line | Prestige Antibodies® Powered by Atlas Antibodies |
| form | buffered aqueous glycerol solution |
| species reactivity | human, mouse, rat |
| technique(s) | immunoblotting: 0.04-0.4 μg/mL,immunohistochemistry: 1:50-1:200 |
| immunogen sequence | HLVLSPPPPHTGPALISALNILEGFNLTSLVSREQALHWVAETLKIALALASRLGDPVYDSTITESMDDMLSKVEAAYLRGHINDSQAAPAPLLPVYELDGAPTAAQVLIMGPDDFIVAMVSSLNQPFGSGLITPSGILLNS |
| web metadata keyword.default | Anti-GGT7 Prestige Antibody immunoblotting,Anti-GGT7 antibody HPA validated,Anti-GGT7 antibody Sigma-Aldrich rabbit,Anti-GGT7 antibody application immunohistochemistry,Anti-GGT7 antibody direct,Anti-GGT7 antibody for western blotting,Anti-GGT7 antibody high purity for research,Anti-GGT7 antibody price for labs,Anti-GGT7 antibody,Anti-Gamma-glutamyltransferase 4 antibody rabbit,Anti-Gamma-glutamyltransferase-like 3 antibody,Prestige Anti-GGT7 antibody immunohistochemistry,immunofluorescence Anti-GGT7 antibody,rabbit Anti-GGT7 antibody 1:50 dilution |
| UniProt accession no. | Q9UJ14 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GGT7(2686) |
