General description
CD21 antigen, also known as complement receptor type 2 (CR2), is a glycoprotein and a receptor for the C3d fragment of complement component 3. It is predominantly expressed in follicular dendritic cells and B lymphocytes. CD21 binds to CD19, and CD81 to form a B cell complex on mature B cells and enhances the B cell response to antigen through C3d.
Immunogen
Synthetic peptide derived from the C-terminus of human CD21 protein.
Features and Benefits
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Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| recombinant | expressed in proprietary host |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | SP186, monoclonal |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | mouse |
| technique(s) | flow cytometry: 1:100,immunoblotting: 1:400,immunohistochemistry: 1:100 |
| isotype | IgG |
| UniProt accession no. | P20023 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CR2(1380) |
