产品介绍
Product Description
Biochem/physiol Actions
6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir alafenamide. 6-Methylflavone is a positive allosteric modulator (PAM) of α1β2γ2L and α1β2 GABAA receptors.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| mp | 119-122 °C (dec.) (lit.) |
| solubility | DMSO: 2 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | Cc1ccc2OC(=CC(=O)c2c1)c3ccccc3 |
| InChI | 1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3 |
| InChI key | NOQJBXPAMJLUSS-UHFFFAOYSA-N |
