产品介绍
Product Description
General description
Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity.
Biochem/physiol Actions
Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells.
Physical form
Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS.
Analysis Note
The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells.
技术参数
Specifications
| biological source | human |
| Quality Level | 100 |
| recombinant | expressed in E. coli |
| assay | ≥98% (SDS-PAGE and HPLC) |
| form | lyophilized powder |
| potency | ≤1.0 ng/mL |
| mol wt | 17.6 kDa |
| packaging | pkg of 5 μg |
| storage condition | avoid repeated freeze/thaw cycles |
| technique(s) | cell culture | mammalian: suitable |
| impurities | endotoxin, tested |
| web metadata keyword.default | primative hematopoietic cells, progenitor cells |
| UniProt accession no. | P36888 |
| storage temp. | −20°C |
| Gene Information | human ... FLT3(2322) |
