产品介绍
Product Description
Application
6-Fluoromevalonate has been used as a mevalonate pyrophosphate decarboxylase inhibitor:
- to study the effect of mevalonate pathway inhibition on patient-derived brain tumor-initiating cells (BTICs) growth and self-renewal
- to study its effect on induction of trained immunity by β-glucan in monocytes
- to determine the effect of the mevalonate pathway (MVP) on ADP-ribosylation factor 6 (ARF6) activation
Biochem/physiol Actions
Mevalonate-pyrophosphate decarboxylase inhibitor
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥90% (GC) |
| form | viscous liquid |
| color | yellow tint |
| solubility | DMSO: ≥3 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | OC1(CF)CCOC(=O)C1 |
| InChI | 1S/C6H9FO3/c7-4-6(9)1-2-10-5(8)3-6/h9H,1-4H2 |
| InChI key | DPPMVKMESJJAJZ-UHFFFAOYSA-N |
