产品介绍
Product Description
General description
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
Immunogen
A synthetic phosphorylated peptide around of human Phospho-POLR2A-S7.
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
技术参数
Specifications
| biological source | rabbit |
| Quality Level | 100 |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | liquid |
| species reactivity | human, rat, mouse |
| concentration | 0.68 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | P24928 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer7 ) |
| Gene Information | human ... POLR2A(5430) |
