产品介绍
Product Description
General description
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM
Immunogen
ACVR1C (AAH22530.1, 23 a.a. ~ 112 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPM
Physical form
Solution in phosphate buffered saline, pH 7.4
技术参数
Specifications
| biological source | mouse |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 2E3, monoclonal |
| form | buffered aqueous solution |
| mol wt | antigen ~35.9 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable,proximity ligation assay: suitable |
| isotype | IgG2aκ |
| NCBI accession no. | BC022530 |
| UniProt accession no. | Q8NER5 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ACVR1C(130399) |
