General description
C-C motif chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein (MIP)-3β, is encoded by the gene mapped to human chromosome 9. The encoded protein is specifically expressed in lymphoid tissues.
The Mouse MIP-3-β (Macrophage Inflammatory Protein 3 β) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MIP-3- β in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Mouse MIP-3 β
Application
请参考Protocol了解详情。
Biochem/physiol Actions
C-C motif chemokine ligand 19 (CCL19) acts as a chemoattractant for T and B lymphocytes, dendritic cells, macrophage progenitor cells and natural killer cells. Therefore, this protein might play an essential role in migration of T cells in the thymus and transfer of T and B cells to secondary lymphoid organs. Overexpression of MIP-3 β (macrophage inflammatory protein-3β)/ C-C motif chemokine ligand 19 (CCL19) leads to pulmonary sarcoidosis.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
| species reactivity | mouse |
| packaging | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable,capture ELISA: suitable |
| input | sample type serum sample type cell culture supernatant(s) sample type plasma |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 5 pg/mL standard curve range: 4.1-1000 pg/mL |
| detection method | colorimetric |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | mouse ... Ccl19(24047) |
