产品介绍
Product Description
Application
Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.
Biochem/physiol Actions
EGFR tyrosine kinase inhibitor.
Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
Features and Benefits
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Preparation Note
5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.
技术参数
Specifications
| biological source | synthetic (organic) |
| Quality Level | 200 |
| assay | ≥98% |
| form | powder |
| potency | 0.8 μM IC50 |
| solubility | DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red |
| storage temp. | 2-8°C |
| SMILES string | NC(\C(=C\c1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N |
| InChI | 1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+ |
| InChI key | JKNOYWVMHPMBEL-UNXLUWIOSA-N |
| Gene Information | human ... CDK2(1017), EGFR(1956) |
