产品介绍
Product Description
Biochem/physiol Actions
anti-inflammatory, anti-parasitic and antifungal pyrancoumarin
Seselin is an anti-inflammatory, anti-parasitic and antifungal pyrancoumarin found in anise and other plants. It appears that seselin targets Jak2 to block the proinflammatory phenotype of macrophages in models of sepsis. Seselin down-regulates levels of proinflammatory factors and activity of STAT1 and p65 in models of sepsis.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | [o]1c2c(ccc3c2C=CC(O3)(C)C)cc[c]1=O |
| InChI | 1S/C14H12O3/c1-14(2)8-7-10-11(17-14)5-3-9-4-6-12(15)16-13(9)10/h3-8H,1-2H3 |
| InChI key | QUVCQYQEIOLHFZ-UHFFFAOYSA-N |
