General description
BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) gene codes for a transmembrane glycoprotein which is a pseudo receptor belonging to the family of TGF-β (transforming growth factor β receptor) type I receptors. BAMBI is predominantly expressed in placenta, spleen and kidney medulla and also found liver, prostate, gut and kidney cortex.
This ELISA antibody pair detects Human BAMBI. Other species not yet determined.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) acts as an inhibitor of TGF-β (transforming growth factor β receptor) signalling which causes epithelial-mesenchymal transition. Upregulation of BAMBI gene is observed in chronic obstructive pulmonary disease and a number of cancer including thyroid, liver, colorectal cancer and ovarian cancer. BAMBI might regulate the events of inflammation and remodeling processes.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
| species reactivity | human |
| technique(s) | ELISA: suitable |
| input | sample type plasma sample type serum sample type cell culture supernatant(s) |
| assay range | inter-assay cv: <12% intra-assay cv: <10% |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... BAMBI(25805) |
