产品介绍
Product Description
Biochem/physiol Actions
Potent inhibitor of CDK5/p25 (IC50=64 nM). Inhibits CDK2/cyclin E at slightly higher concentration (IC50=98nM) (1). Protects cells against NAC-amyloid-induced cell death (2). Cell permeable. MW=260.4. Purity ?95% by TLC. Formulated as a lyophilized powder. May be dissolved in DMSO (>25 mg/mL) or DMF (30 mg/mL). Stable desicated as supplied at ambient temperature for up to 2 years, or in solution at -20°C for up to 2 months.
Preparation Note
Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 2 months.
技术参数
Specifications
| assay | >95% (TLC) |
| form | lyophilized powder |
| mol wt | ~260.4 |
| shipped in | ambient |
| storage temp. | −20°C |
