产品介绍
Product Description
Application
磺溴酞二钠盐水合物已用作阳性对照，以研究11-酮-β-乳香酸（KBA）和3-乙酰基-11-酮-β-乳香酸（AKBA）与有机阴离子转运蛋白OATP1B3的相互作用。
Biochem/physiol Actions
磺溴酞（BSP）是有机阴离子转运多肽（OATP）的高亲和力有机离子底物，已被用作多药耐药相关蛋白2（Mrp2）的底物。BSP通过OATP转运到肝细胞中，与谷胱甘肽结合后，通过MRP2排泄到胆汁中。发现它抑制醛酮还原酶ARK1C20。
技术参数
Specifications
| Quality Level | 200 |
| form | powder |
| composition | Water (by Karl Fischer): ≤ 8% Sodium (Na) anhydrous: 4.6-5.8% |
| technique(s) | titration: suitable |
| color | white to light gray |
| solubility | water: 50 mg/mL (clear to very hazy) |
| λmax | 575-581 nm |
| application(s) | diagnostic assay manufacturing hematology histology |
| storage temp. | room temp |
| SMILES string | [Na+].[Na+].[H]O[H].Oc1ccc(cc1S([O-])(=O)=O)C2(OC(=O)c3c(Br)c(Br)c(Br)c(Br)c23)c4ccc(O)c(c4)S([O-])(=O)=O |
| InChI | 1S/C20H10Br4O10S2.2Na.H2O/c21-15-13-14(16(22)18(24)17(15)23)20(34-19(13)27,7-1-3-9(25)11(5-7)35(28,29)30)8-2-4-10(26)12(6-8)36(31,32)33;;;/h1-6,25-26H,(H,28,29,30)(H,31,32,33);;;1H2/q;2*+1;/p-2 |
| InChI key | CDTNUNQQEUGDSD-UHFFFAOYSA-L |
